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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKM
All Species:
29.09
Human Site:
S178
Identified Species:
45.71
UniProt:
P06732
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06732
NP_001815.2
381
43101
S178
G
K
Y
Y
P
L
K
S
M
T
E
K
E
Q
Q
Chimpanzee
Pan troglodytes
XP_001163660
381
42901
S178
V
P
H
C
S
H
R
S
M
T
E
K
E
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001112108
381
42634
S178
G
R
Y
Y
A
L
K
S
M
T
E
A
E
Q
Q
Dog
Lupus familis
XP_533641
488
54723
S285
G
K
Y
Y
P
L
K
S
M
T
E
Q
E
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
P07310
381
43026
S178
G
K
Y
Y
P
L
K
S
M
T
E
Q
E
Q
Q
Rat
Rattus norvegicus
P07335
381
42707
S178
G
R
Y
Y
A
L
K
S
M
T
E
A
E
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508143
326
36755
F170
W
H
N
D
N
K
T
F
L
V
W
I
N
E
E
Chicken
Gallus gallus
P00565
381
43310
A178
G
R
Y
Y
P
L
K
A
M
T
E
Q
E
Q
Q
Frog
Xenopus laevis
NP_001080073
381
42887
D178
G
K
Y
Y
P
L
K
D
M
S
D
A
E
Q
Q
Zebra Danio
Brachydanio rerio
NP_571007
381
42806
S178
G
K
Y
Y
P
L
K
S
M
T
D
A
E
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
A176
P
L
T
G
M
E
K
A
V
Q
Q
Q
L
I
D
Honey Bee
Apis mellifera
O61367
355
39990
T176
L
T
G
M
S
K
E
T
Q
Q
K
L
I
D
D
Nematode Worm
Caenorhab. elegans
Q27535
360
40364
E180
P
L
T
G
M
D
E
E
T
K
K
K
L
I
A
Sea Urchin
Strong. purpuratus
P18294
1174
130851
G592
G
K
Y
Y
P
L
E
G
M
S
D
E
T
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169054
381
42707
S178
G
R
Y
Y
A
L
K
S
M
T
E
A
E
Q
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
80.5
75.1
N.A.
96.5
79.5
N.A.
70.3
90.2
88.7
88.7
N.A.
42.5
40.4
37.5
22.4
Protein Similarity:
100
97.3
90.2
77.4
N.A.
98.9
89.5
N.A.
78.2
95.8
95.5
94.2
N.A.
58.7
59
55.3
27.8
P-Site Identity:
100
53.3
80
93.3
N.A.
93.3
80
N.A.
0
80
73.3
80
N.A.
6.6
0
6.6
53.3
P-Site Similarity:
100
66.6
86.6
100
N.A.
100
86.6
N.A.
20
100
86.6
93.3
N.A.
33.3
20
20
80
Percent
Protein Identity:
N.A.
79.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
89.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
80
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
0
14
0
0
0
34
0
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
0
7
0
0
20
0
0
7
14
% D
% Glu:
0
0
0
0
0
7
20
7
0
0
54
7
67
7
14
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
67
0
7
14
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
7
7
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
7
14
0
% I
% Lys:
0
40
0
0
0
14
67
0
0
7
14
20
0
0
0
% K
% Leu:
7
14
0
0
0
67
0
0
7
0
0
7
14
0
0
% L
% Met:
0
0
0
7
14
0
0
0
74
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
14
7
0
0
47
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
14
7
27
0
74
60
% Q
% Arg:
0
27
0
0
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
14
0
0
54
0
14
0
0
0
0
0
% S
% Thr:
0
7
14
0
0
0
7
7
7
60
0
0
7
0
7
% T
% Val:
7
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
67
67
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _